Elise Lander

• Lander, Elise; Hamarsland, Håvard; Lees, M. J.; Moore, D. & Raastad, Truls (2026). Resistance training partially restores age-related differences in skeletal muscle amino acid transporters - secondary analysis from two randomized controlled trials. The Journal of Nutrition, Health & Aging. ISSN 1279-7707. 30(4). doi: 10.1016/j.jnha.2026.100808. Fulltekst i vitenarkiv
• Vikmoen, Olav; Teien, Hilde Kristin; Tansø, Rita; Aandstad, Anders; Lander, Elise & Cumming, Kristoffer Toldnes [Vis alle 9 forfattere av denne artikkelen] (2024). Effects of a 10-d Military Field Exercise on Body Composition, Physical Performance, and Muscle Cells in Men and Women. Medicine & Science in Sports & Exercise. ISSN 0195-9131. 56(4). doi: 10.1249/MSS.0000000000003340. Fulltekst i vitenarkiv Vis sammendrag

  Purpose:To investigate the effects of a demanding military field exercise on physical performance, body composition and muscle cellular outcomes in men and women.Methods:Ten men (20.5 ± 0.5 years) and 8 women (21.4 ± 1.4 years) completed a 10-day field exercise consisting of extensive physical activity with food and sleep restriction. Acquisition of body composition, physical performance, blood and muscle biopsies samples were done before and 1,7 and 14 days after the exercise.Results:There were no sex differences in the response to the exercise. Body mass was decreased with 5.6 ± 1.8% and fat mass with 31 ± 11% during the exercise. Both were still reduced after 14 days (2.5 ± 2.3%, p˂0.001 and 12.5 ± 7.7%, p˂0.001 respectively). Isometric leg strength did not change. Peak leg extension torque at 240 °·s-1 and counter movement jump height were reduced with 4.6 ± 4.8% (p = 0.012) and 6.7 ± 6.2% (p˂0.001) respectively and was still reduced after 14 days (4.3 ± 4.2%, p = 0.002, and 4.1 ± 4.7%, p = 0.030). No changes occurred in fiber CSA, fiber types, proteins involved in calcium handling or HSP70. During the exercise, αB-crystallin levels decreased by 14 ± 19% (p = 0.024) in the cytosolic fraction and staining intensity on muscle sections tended to increase (17 ± 25%, p = 0.076). MuRF1 levels in the cytosolic fraction tended to decrease (19 ± 35%) and increased with 85 ± 105% (p = 0.003) in the cytoskeletal fraction 1 week after the exercise.Conclusions:The field exercise resulted in reduced body mass and physical performance in both sexes. The ability to produce force at high contraction velocities and explosive strength was more affected than isometric strength, but this was not related to any changes in fiber type composition, fiber area, Ca2+ handling or fiber type specific muscle damage.

• Lander, Elise; Kirkhus, Bente; Lindberg, Diana & Raastad, Truls (2023). Aminoacidemia after ingestion of protein hydrolysate produced from poultry carcasses: A comparison against whey protein in a randomized, double-blinded cross-over study in healthy young and old individuals. Journal of Functional Foods. ISSN 1756-4646. 102, s. 1–10. doi: 10.1016/j.jff.2023.105452. Fulltekst i vitenarkiv Vis sammendrag

  This study investigated the aminoacidemia after ingestion of a poultry protein hydrolysate (PPH) and whey protein in healthy young and old participants. Protein-drinks were also digested using the INFOGEST static in vitro digestion model to simulate gastrointestinal changes in young and old adults. In fasted state, 10 young (20-40y) and 10 old (70-80y) ingested PPH or whey as a 20 g protein-drink and blood samples were collected. Plasma leucine concentration increased more when ingesting whey than PPH (young 62 ± 27 vs. 48 ± 27%, old 94 ± 57 vs. 66 ± 26%) but the peak concentration was reached faster after drinking PPH (p < 0.05). The in vitro digestion of PPH was consistent with the observed changes in plasma amino acid concentrations, but whey digestibility was lower under ageing conditions. These results show that PPH is rapidly digested and absorbed due to the hydrolysis into short peptide chains, and that healthy elderly have similar absorption as younger individuals.

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• Vikmoen, Olav; Teien, Hilde Kristin; Tansø, Rita; Aandstad, Anders; Lander, Elise & Cumming, Kristoffer Toldnes [Vis alle 8 forfattere av denne artikkelen] (2025). SEX DIFFERENCES IN CYCLING EFFICIENCY, AEROBIC ENZYMES, AND GLYCOGEN STORES FOLLOWING A STRENUOUS MILITARY FIELD EXERCISE. Fulltekst i vitenarkiv Vis sammendrag

  Introduction Strenuous military field exercises (MFE) causes muscle mass loss and long-lasting physical performance impairments. However, their effect on muscle efficiency during submaximal work and associated cellular muscle changes are poorly understood. Furthermore, the effects of MFE in women are not well documented. This study aimed to investigate the impact of strenuous MFE on efficiency during submaximal work, muscle aerobic enzyme content, muscle glycogen content, and to identify potential sex differences in these aspects. Methods Efficiency was tested on a cycle ergometer (200 W for men and 150 W for women) and CMJ on a force plate in 10 men and in 8 women before (T0), and 1 (T1), 7 (T7), and 14 (T14) days after a 10-days MFE consisting of rigorous physical activity with food and sleep restriction. Muscle biopsies from m. vastus lateralis were collected at T0, T1, and T7. Results Countermovement jump height was decreased with 6.7±6.2% (p≤0.001) at T1 and was still decreased at T14 with 4.1±4.7% (p=0.003) for the sexes combined. There were no sex differences in the changes from T0 The men improved gross efficiency (GE) at T1 (0.7±0.7 pp, p=0.019), whereas it decreased in women (–0.9±1.0 pp, p=0.042). The change was different between sexes (p=0.002), and these group differences persisted at T7 (p=0.022). At T14, GE returned to pre-values in women, while it remained improved in men (0.4±0.6 pp, p=0.038), with no sex differences in the changes from T0. Heart rate (HR) decreased at T1 in both men (–12.9±3.4%, p≤0.001) and women (–4.6±4.7%, p=0.030), with a larger reduction in men (p≤0.001). HR remained reduced in men throughout recovery but returned to pre-values at T7 in women. Blood lactate concentration did not change significantly in either sex, though women showed a larger (p=0.037) non-significant increase at T1 (29±44%, p=0.198) compared to a non-significant decrease in men (–11±31%, p = 0.109). There were no sex differences in changes in respiratory exchange ratio or perceived exertion during submaximal cycling. At T7, the sexes combined reduced the content of citrate synthase (–23±28%, p=0.005) and tended to reduce to content of COX4 (–18±43%, p=0.056), with no sex differences. The changes in muscle glycogen content were similar in Type I and II fibers for both sexes. At T1, glycogen content in the muscle fibers combined was reduced in both men and women with 8±10% (p=0.033) and 8±8% (p=0.02), respectively. At T7, the percentage change from T0 was different between sexes (p=0.009), where the men had increased glycogen content with 10±6% (p≤0.001), while the women returned to T0 values. Conclusion A demanding MFE resulted in improved cycling efficiency in men but impaired efficiency in women. The reasons for this sex difference remain unclear, though it is likely unrelated to changes in aerobic enzyme levels or glycogen stores, which were similar between men and women.

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