Despite the fact that focal cartilage lesions have been recognized a cause of significant morbidity for more than 200 years and that surgical techniques have been widely used for more than 50 years, the evidence of the effects of rehabilitation after focal cartilage lesions and after surgical cartilage repairs is more or less absent.
Active rehabilitation for patients with cartilage lesions. A new approach to rehabilitation after cartilage lesions and cartilage repair
To describe and evaluate symptoms and function after a three month active rehabilitation program for patients with focal cartilage lesions in the knee used either as a preoperative rehabilitation program or as a stand-alone rehabilitation program.
To investigate the effect of different weight bearing modalities on functional and radiographic outcome two years after cartilage repair.
To evaluate the long term effect of different weight bearing modalities on functional, radiographic and molecular biological outcome five years after cartilage repair.
To evaluate the validity and responsiveness of two different patient-reported outcome measurements for patients with focal cartilage lesions.
Two different patient cohorts will be included to answer the research questions. A RCT will examine the effect of different weight bearing modalities on clinical and radiographic outcome in patients treated with the MACI technique on the medial femoral condyle.
The second cohort comprises patients with full thickness cartilage lesions in the tibiofemoral condyle. These patients will perform a three-month active rehabilitation program including cardiovascular training, knee and hip muscle strength training and neuromuscular training. The feasibility and changes of knee function will be evaluated.
“Effect of accelerated weight-bearing after MACI on the femoral condyle on radiographic and clinical outcome after 2 years”; Am J Sports Med 2009, 37:88S
“The feasibility of a 3-month active rehabilitation program for patients with knee full-thickness articular cartilage lesions: the Oslo Cartilage Active Rehabilitation and Education Study”; JOSPT 2013, 43(5)