Prognostic factors and knee function in surgically and non-surgically treated patients with anterior cruciate ligament rupture

There is a lack of knowledge on clinical outcomes and prognosis after surgical and non-surgical treatment of anterior cruciate ligament injury. It is of particular interest to compare long-term outcomes and early prognostic factors in the two treatment groups. Increased knowledge on this area can improve the knowledge base for treatment and thus patient outcomes.

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Formal title

Prognostic factors and knee function in surgically and non-surgically treated patients with anterior cruciate ligament rupture

Formal

The objectives of this PhD project is to:

1. Compare patient-reported outcomes and describe radiographic features present at 5 years after surgical and non-surgical treatment of individuals with ACL rupture.
2. Conduct a systematic review of prognostic factors for PROMs and physical activity level ≥ 2 and < 10 years after ACL injury both in those treated surgically and those treated non-surgically.
3. Identify prognostic factors for 5-year outcomes in surgically and non-surgically treated patients with ACL-rupture

4. Asses return to pivoting sports as a risk factor for 5-year presence of radiographic features in surgically and non-surgically treated patients with ACL-rupture

Description

The project is a 5-year follow-up of the 300 participants in the "Delaware-Oslo ACL Cohort Study", which is a prospective cohort study. Patients were included between 2007 and 2012 and 5-year data collection was completed in 2017. Patients underwent a 5-week rehabilitation period before a surgical or non-surgical treatment choice were made. Everyone underwent high quality rehabilitation programs. All patients were tested with a comprehensive test battery at inclusion and after the rehabilitation period. Further follow-ups were performed at 6 months, 1 year, 2 years and 5 years after inclusion/surgery depending on treatment choice. Activity level was recorded monthly during the first two years.