The impact on athletic performance, doping legislation and life-long health
In the seminar, further insights into the cellular mechanisms, how they impact regulation of muscle mass and function, and how this affects human performance and health will be further discussed.
Muscle memory describes the capacity of skeletal muscle fibers to respond differently to environmental stimuli in an adaptive (positive) or maladaptive (negative) manner if the stimuli have been previously encountered.
Within strength training muscle memory refers to the phenomenon where previously trained muscles re-gain muscle size and strength faster than naive muscles after a period of disuse. The cellular memory mechanisms seem to involve accretion of more nuclei within each muscle fiber as well as epigenetic modifications altering the access to important regulatory genes.
Doping with anabolic steroids gives some of the same long-lasting memory effects as previous exercise and this information should impact the rules for suspension after a positive doping test.
08:15 - 08:30 Coffee served outside Auditorium Utsikt
08:30 - 08:40 Welcome and overview of muscle memory (Truls Raastad, NIH)
08:40 - 09:00 Mechanisms for muscle memory: Evidence from animal studies and implications for doping legislations (Kristian Gundersen, UiO)
09:00 - 09:15 How DNA content influences muscle cell size during muscle growth and hypertrophy (Einar Eftestøl, UiO)
09:15 - 09:35 The epigenetics of skeletal muscle memory (Adam Sharples, NIH)
09:35 - 09:45 Is there a negative muscle memory with repeated immobilization? (Daniel Turner, NIH)
09:45 - 10:00 Questions and discussion